THE INFLUENCE OF ULTRA-WIDEBAND LOW-INTENSITY ULTRASOUND ON THE FUNCTIONAL ACTIVITY OF PERITONEAL MACROPHAGES IN VITRO

Aleksandr Kuzmenko; Aleksandr Marchenko; Karl Volokh

doi:10.36074/grail-of-science.07.06.2024.038

THE INFLUENCE OF ULTRA-WIDEBAND LOW-INTENSITY ULTRASOUND ON THE FUNCTIONAL ACTIVITY OF PERITONEAL MACROPHAGES IN VITRO

Authors

Aleksandr Kuzmenko Dragomanov state university of Ukraine, Ukraine https://orcid.org/0000-0002-2711-3027
Aleksandr Marchenko Evolus Technologies LTD, Haifa
Karl Volokh Techno-Med Ukraine, Ukraine

DOI:

https://doi.org/10.36074/grail-of-science.07.06.2024.038

Keywords:

ultra-wideband low-intensity burst ultrasound (UMUS), low-intensity narrowband pulsed ultrasound (LIPUS), functional activity of macrophages

Summary

Studies have been conducted on the influence of various modes of ultrasound on the functional activity of peritoneal macrophages in nitro. It was found that the use of low-intensity broadband ultrasound (UMUS) significantly increases the cytotoxic and respiratory activity of macrophages compared to low-intensity pulsed ultrasound (LIPUS) and control. There was a significant increase in the level of endogenous peroxidase in the macrophage lysate, as well as a transition of macrophages from the M1 (pro-inflammatory) to M2 (anti-inflammatory) state when using UMUS.

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References

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